Troopers were called to 5700 State Route 145 in the Town of Seward shortly before 9:00 p.m. on Thanksgiving after the home exploded.  Troopers assisted the Schoharie County Fire Coordinator and his team at the scene.  The residence is unoccupied and no one was inside at the time of the explosion.  No injuries resulted from the blast.  The Sharon Fire Department responded to the scene.  The investigation into the incident is continuing.